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Ishihara's students suffer from serious illnesses like leukemia, kidney disorders, asthma and diabetes. On his first day at school, Ishihara wears a 'red nose' and attempts to amuse them but it only makes one of the students' condition worse.
After noticing Wada is in love with a girl in another ward, Ishihara meddles in his affairs and makes the girl attend the in house class. Contrary to his expectation, Wada gets angry and runs out of the classroom.
Unlike Tagawa, the harder Ishihara tries to make the students laugh, the more he fails. To have at least one student like him, he makes an effort to get along with Tanaka, but she ignores him and throws her manga out of the window.